Publications


Department of Regenerative Medicine and Biomedical Engineering,
Faculty of Medicine,Saga University

2019

Takeuchi H, Ikeguchi R, Aoyama T, Oda H, Yurie H, Mitsuzawa S, Tanaka M, Ohta S, Akieda S, Miyazaki Y, Nakayama K, Matsuda S.
"A scaffold-free Bio 3D nerve conduit for repair of a 10-mm peripheral nerve defect in the rats. "
Microsurgery. 2019 Nov 14.

 

Kitsuka T, Itoh M, Amamoto S, Arai K, Oyama J, Node K, Toda S, Morita S, Nishida T, Nakayama K
" 2-Cl-C.OXT-A Stimulates Contraction through the Suppression of Phosphodiesterase Activity in Human Induced Pluripotent Stem Cell-derived Cardiac Organoids"
PLoS ONE July 2019

 

Mitsuzawa S, Ikeguchi R, Aoyama T, Takeuchi H, Yurie H, Oda H, Ohta S, Ushimaru M, Itho T , Tanaka M, Kunitomi Y, Tsuji M , Akieda S, Nakayama K, Matsuda S
"The efficacy of a scaffold-free Bio 3D conduit developed from autologous dermal fibroblasts on peripheral nerve regeneration in a canine ulnar nerve injury model : a preclinical proof of concept study"
Cell Transplantation Vol 28, Issue 9-10, 2019

 

Itoh M, Mukae Y, Kitsuka T, Arai K, Nakamura A, Uchihashi K, Toda S, Matsubayashi K, Oyama J, Node K, Kami D, Gojo S, Morita S, Nishida T, Nakayama K*, and Kobayashi E* *Co-corresponding author
"Development of an immunodeficient pig model allowing long-term accommodation of artificial human vascular tubes"
Nature Communications 2019 May 21;10(1):2244.

 

Nakanishi Y, Okada T, Takeuchi N, Kozono N, Senjyu T, Nakayama K, Nakashima Y
"Histological evaluation of tendon formation using a scaffold-free three-dimensional-bioprinted construct of human dermal fibroblasts under in vitro static tensile culture"
Regenerative Therapy Volume 11, December 2019, Pages 47-55

 

Taguchi T, Yanagi Y, Yoshimaru K, Zhang X, Matsuura T, Nakayama K, Kobayashi K, Yamaza H, Nonaka K, Ohga S
"Regenerative medicine using stem cells from human exfoliated deciduous teeth (SHED): a promising new treatment in pediatric surgery."
Surgery today 49 (4), 316-322

 

Takeoka Y, Matsumoto K, Taniguchi D, Tsuchiya T, Machino R, Moriyama M, Oyama S, Tomoyuki T, Taura Y, Takagi K, Yoshida T,Matsuo N, Abdelmotagaly Elgalad, Kunizaki M,Tobinaga S, Nonaka T, Hidaka S,Yamasaki N, Nakayama K, Nagayasu T
"Regeneration of esophagus using a scaffold-free biomimetic structure created with biothree-dimensional printing."
PLoS ONE March 14(3): e021133

 

Machino R, Matsumoto K, Taniguchi D, Tsuchiya T, Takeoka Y, Taura Y, Moriyama M, Tetsuo T, Oyama S, Takagi K, Miyazaki T, Hatachi G, Doi R, Shimoyama K, Matsuo N, Yamasaki N, Nakayama K, Nagayasu T
"Replacement of Rat Tracheas by Layered, Trachea-like, Scaffold-free Structures of Human Cells Using Bio-3D Printing System."
Adv . Healthcare Mater . 2019, 1800983

 

Oshima T, Nakase J, Toratani T, Numata H, Takata Y, Nakayama K, Tsuchiya H
"A Scaffold-Free Allogeneic Construct From Adipose-Derived Stem Cells Regenerates an Osteochondral Defect in a Rabbit Model"
Arthroscopy: The Journal of Arthroscopic & Related Surgery 35 (2), 583-593

 

2018

Arai K, Murata D, Ana R.Verissimo, Mukae Y, Itoh M, Nakamura A, Morita S and Nakayama K.
"Fabrication of scaffold-free tubular cardiac constructs using a bio-3D printer, "
PLoS ONE Decmber 13(12): e0209162. 

 

Mukae Y, Itoh M, Noguchi R, Furukawa K, Arai KI, Oyama JI, Toda S, Nakayama K, Node K, Morita S.
"The addition of human iPS cell-derived neural progenitors changes the contraction of human iPS cell-derived cardiac spheroids."
Tissue Cell. 2018 Aug;53:61-67. doi: 10.1016/j.tice.2018.05.002. Epub 2018 May 5.

 

Murata D,Akieda S,Misumi K, Nakayama K.
"Osteochondral regeneration with a scaffold-free three-dimensional construct of adipose tissue-derived mesenchymal stromal cells in pigs."
Tissue Engineering and Regenerative Medicine February 2018,15(1)101-113

 

Taniguchi D, Matsumoto K, Tsuchiya T, Machino R, Takeoka Y, Elgalad A, Gunge K, Takagi K, Taura Y, Hatachi G, Matsuo N, Yamasaki N, Nakayama K, Nagayasu T.
"Scaffold-free trachea regeneration by tissue engineering with bio-three-dimensional printing"
Interactive Cardiovascular and Thoracic Surgery, April 2018,26(4)713

 

Xiu-Ying Zhang, Yanagi Y, Zijing Sheng, Nagata K, Nakayama K, Taguchi T.
"Regeneration of diaphragm with bio-3D cellular patch"
Biomaterials June 2018, 167:1-14      

 

J Groll, J A Burdick, D-W Cho, B Derby, M Gelinsky, S C Heilshorn, T Jüngst, J Malda, V A Mironov,  Nakayama K, A Ovsianikov, W Sun,Takeuchi S, J J Yoo, T B F Woodfield
"A definition of bioinks and their distinction from biomaterial inks"
Biofabrication 11 013001 (Perspective)

 

2017

Yurie H, Ikeguchi R, Aoyama T, Kaizawa Y, Tajino J, Ito A, Ohta S, Oda H, Takeuchi H, Akieda S, Tsuji M, Nakayama K, Matsuda S.
"The efficacy of a scaffold-free bio 3D conduit developed from human fibroblasts on peripheral nerve regeneration in a rat sciatic nerve model "
PLoS One February 13,2017,12(2): e0171448

 

Toratani T, Nakase J, Numata H, Oshima T, Takata Y, Tsuchiya H, Nakayama K.
"Scaffold-free tissue-engineered allogenic adipose-derived stem cells promote meniscus healing." 
Arthroscopy:The Journal of Arthroscopic and Related Surgery, February 2017,33(2):346-354

 

Moldovan N.I., Hibino N, Nakayama K.
"Principles of the 'Kenzan' method for robotic cell spheroid-based three-dimensional bioprinting."
Tissue Engineering Part B:Reviews,June 2017,23(3)237-244 (Review)


Yanagi Y, Nakayama K, Taguchi T, Enosawa S, Tamura T, Yoshimaru K, Matsuura T, Hayashida M, Kohashi K, Oda Y, Yamaza T, Kobayashi E.
"In vivo and ex vivo methods of growing a liver bud through tissue connection"
Scientific Reports October 26 2017,7(1)14085

 

Verissimo A.R., Nakayama K.
"Scaffold-Free Biofabrication. "
3D Printing and Biofabrication. Reference Series in Biomedical Engineering. Springer (Chaptor)

 


2016

Noguchi R, Nakayama K, Itoh M, Kamohara K, Furukawa K, Oyama J, Node K, Morita S.
"Development of a three-dimensional pre-vascularized scaffold-free contractile cardiac patch for treating heart disease."
The Journal of Heart and Lung Transplantation
January 2016, 35(1),137-145

 

2015

Murata D, Tokunaga S, Tamura T, Kawaguchi H, Miyoshi N, Fujiki M, Nakayama K,
Misumi K.
"A preliminary study of osteochondral regeneration using a scaffold-free three-dimensional construct of porcine adipose tissue-derived mesenchymal stem cells. "
Journal of Orthopaedic Surgery and Research 2015 Mar. 18;10:35

 

 

Itoh M, Nakayama K, Noguchi R, Kamohara K, Furukawa K, Uchihashi K, Toda S, Oyama J,  Node K, Morita S.
"Scaffold-free tubular tissues created by a Bio-3D printer undergo remodeling and endothelialization when implanted in rat aortae."
PLOS ONE September 1, 2015, 10(9): e0136681

 

2014

Murata D, Miyakoshi D, Hatazoe T, Miura N, Tokunaga S, Fujiki M, Nakayama K, Misumi K.
"Multipotency of equine mesenchymal stem cells derived from synovial fluid."
The Veterinary Journal, 2014 Oct, 202(1):53-61

 

Ishihara K, Nakayama K, Akieda S, Matsuda S, Iwamoto Y.
"Simultaneous regeneration of full-thickness cartilage and subchondral bone defects in vivo using a three-dimensional scaffold-free autologous construct derived from high-density bone marrow-derived mesenchymal stem cells"
Journal of Orthopaedic Surgery and Research 2014 Oct. 14;9:98

 

2013

K Nakayama
"In Vitro Biofabrication of Tissues and Organs"
Biofabrication: Micro-and Nano-Fabrication. Printing Patterning and Assemblies. (Chapter)

Shimoto T, Hidaka N, Sasaki H, Nakayama K, Akieda S, Matsuda S, Miura H, Iwamoto Y.
"Bio rapid prototyping project: Development of spheroid formation system for regenerative medicine. "
Information Technology Convergence, 2013, 253(Lecture Notes in Electrical Engineering):855-862 

2012

Shimoto T, Nakayama K, Matsuda S, Iwamoto Y.
"Building of HD MACs using cell processing robot for cartilage regeneration. "
Journal of Robotics and Mechatronics 2012, 24(2):347-353

 

2009

Akasaki Y, Matsuda S, Nakayama K, Fukagawa S, Miura H, Iwamoto Y.
"Mevastatin reduces cartilage degradation in rabbit experimental osteoarthritis through inhibition of synovial inflammation."
Osteoarthritis Cartilage. 2009 Feb;17(2):235-243. 

 

Yoshida T, Sakamoto A., Tsukamoto N., Nakayama K., Iwamoto Y
"Establishment of an animal model of a pasteurized bone graft, with a preliminary analysis of muscle coverage or FGF-2 administration to the graft. "
Journal of Orthopaedic Surgery and Research 2009 Aug 4;4:31

 

2005

Nakayama K, Matsuda S, Miura H, Iwamoto Y, Higaki H, Otsuka K.
"Contact stress at the post-cam mechanism in posterior-stabilised total knee arthroplasty."
The Bone & Joint Journal (formerly known as Journal of Bone and Joint Surgery British Volume)
2005 Apr; 87-B(4):483-488